Both sides opened the season with victory, the Yellows defeating Rushall Olympic 2-0 and newly-promoted Lancaster recording a credible 2-1 win at Buxton.
Yellows boss Paul Carden said: “We’ll go there looking to win. We don’t change our mindset. There might be little tweaks here and there with what we do and how we set up.
“I think we can go anywhere and win. I’m that confident in the squad of players we’ve put together.
“It’ll be a tough game, they had a decent result on Saturday, that’s a great win for them, so it will be a tough game but likewise it will be a tough game for them.”
Lancaster’s squad includes two familiar faces, with midfielders Scott Harries and Ryan Winder in their ranks.
Harries opted to leave the Yellows in the summer due to the travelling commitments, while Winder left mid-season having made the move from Lancaster in 2016.
The Dolly Blues return to the Evo-Stik Premier League this season having been crowned champions of the Evo-Stik League First Division North last year, the same league title Warrington had won 12 months previous.